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Macherey-Nagel

MACHEREY-NAGEL was founded in 1911 in Düren as a specialist manufacturer of filter papers. Since that time, we have evolved into an innovative international company for chemical and biomolecular analysis. MACHEREY-NAGEL stands for innovative and creative solutions which we have a penchant for developing in-house. In addition to the “traditional” departments, such as research, production, sales and media design, we also have departments such as mechanical engineering and device development as well as our own joinery.

Our products are among the world’s most reliable analytical systems. They are used, for example, in industry, healthcare, biotechnology, environmental analysis and research. Numerous patents and international certifications underline the high quality of our products and the competence of our employees.

Nucleic Acid Purification

Your partner for efficient RNA, DNA, and protein purification from diverse sample materials in any format.

Plasmid DNA

As a pioneer in nucleic acid purification technologies, MN has been developing plasmid purification products of the highest quality for about 30 years. Today we offer a comprehensive portfolio of plasmid purification kits enabling the highest purity, excellent yield and very fast processing.

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Clean-up Kits

MACHEREY‑NAGEL’s clean up kits focus on fast, easy to handle, and quantitative high recovery DNA and RNA purification. Based on different purification technologies, you can select the optimal solution for low to high throughput as well as for high quality downstream applications.

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DNA Purification Kits

Combining selective purification technologies and chemistries, we offer a comprehensive range of specialised DNA isolation kits for a broad range of diversified starting materials. The resulting high quality DNA serves as an excellent basis for following demanding downstream applications.

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RNA Purification Kits

Our ready to use kits isolate high quality RNA including small RNA (miRNA) from various sample material with highest lysis efficiency. The handling is convenient and user‑friendly. Take advantage of our experience as RNA experts.

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Viral RNA/DNA

Our viral RNA and DNA isolation kits have been optimised for use with cell‑free biological fluids and diverse veterinary and clinical samples. They are specialised for low viral titers and large sample volumes and are characterised by the highest consistency and sensitivity for different types of viruses.

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Protein

We provide ready to use resins or columns for GST‑tag and His‑tag purification. Our products show market leading performance. Using our protein purification products you can save money without making compromises.

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Catalog Number 11922402

Macherey-Nagel™ NucleoSpin™ RNA, Mini kit for RNA purification

Catalog Number 11992242

Macherey-Nagel™ NucleoSpin™ Gel and PCR Clean-up Kit

Catalog Number 12353358

Macherey-Nagel™ NucleoSpin™ Plasmid DNA

Rapid Tests

Our test papers allow identification or semi-quantitative determination of more than 40 different substances. They give rapid results and are easy to use for an accurate on-site analysis.

pH Tests

A large variety of different pH test paper types is provided by MN:

pH Fix - Nonbleeding pH test strips
pH universal indicator paper - Standard in many applications
PEHANON - pH determination in coloured samples

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Semi Quantitative Test Strips

Test papers and test strips for semi quantitative analysis are extremely simple to handle. They are based on the principle of “Dip&Read”. They are available for a variety of parameters and comply with all requirements of a modern rapid test. The evaluation of these tests is carried out by a comparison with a colour scale.

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Qualitative Test Papers - Without Colour Chart

Qualitative test papers come without a colour scale. With little effort, the presence of ions and other substances can be detected. The test papers change their colour when the concentration is above the specified limit of detection.

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Catalog Number 11807073

Macherey-Nagel™ Quantofix™ Test Strips

Catalog Number 10159960

Macherey-Nagel™ Quantofix™ Peroxide 100 Test Strip Kits

Catalog Number 15364184

Macherey-Nagel™ pH-Fix pH Indicator Strips

Filtration

Premium filter papers, extractions thimbles and membranes for all applications. Consistent in qualit and performance. Filtration solutions, you can rely on.

Cellulose Filters

Ashless filter papers, ashless hardened filter papers, qualitative filter papers, qualitative hardened filter papers, technical filter papers, chromatography papers.

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Glass Fibre Filters

Glass fibre filters without binder, glass fibre filters with binder, quartz fibre filters.

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Extraction Thimbles

Cellulose extraction thimbles, glass fibre extraction thimbles.

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Membranes

Thin, precut membrane rounds for high-throughput, fast filtration of liquid and gas samples.

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Special Filter Products

Weighing aids, phase separation papers, lens paper - José papers, ion exchange papers, antibiotic resistency papers, surface protection papers, filtering aids

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Syringe Filters

For use with polar and nonpolar solvents, especially water and organic solvent mixtures used in TOC/DOC determination.

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Catalog Number 10322861

Macherey-Nagel™ MN 615 Grade Round Format Cellulose Qualitative Filter Paper

Catalog Number 11683079

Macherey-Nagel™ Chromafil™ Xtra PET Polyester Syringe Filters

Catalog Number 10620303

Macherey-Nagel™ Cellulose Extraction Thimbles

MACHEREY-NAGEL Chromatography – Complete Solutions for Your Analysis

We provide optimal and reliable solutions for your laboratory work in sample preparation, method development and routine analysis.

From a pioneer in chromatography to a full-range supplier of laboratory consumables, we supply laboratories around the world with HPLC, GC and SPE columns, TLC/HPTLC plates, autosampler vials, closures and more.

MACHEREY-NAGEL offers a versatile range of ready-to-use TLC and HPTLC layers, which are the result of 50 years of continuous research and development in thin layer chromatography.

The Comprehensive Range of TLC Products

TLC/HPTLC Glass Plates

ADAMANT, SIL G or SIL HD are silica layers on glass backing. It’s hard to imagine a laboratory without our reliable TLC and HPTLC glass plates.

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ALUGRAM and POLYGRAM TLC/HPTLC Sheets

ALUGRAM and POLYGRAM TLC/HPTLC sheets are easy to handle, lightweight and flexible. High performance silica on ALUGRAM Xtra sheets provides outstanding wettability for precise colourisation results. Moreover, these TLC sheets are easy to cut with scissors.

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ALUGRAM and POLYGRAM TLC/HPTLC Sheets Image

Accessories

In addition to high quality TLC plates and sheets, we offer staining reagents and developing chambers, as well as introductory sets for educational purposes.

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TLC Backings and Supports

Glass Plates

Glass plates are robust, heat proof and chemically resistant to all common mobile phases and visualisation reagents. They are the traditional option in TLC/HPTLC and are widely used in the pharmaceutical sector and other laboratory environments.

Thickness (approx.): 1.3mm
Weight and storage requirements: high
Torsional strength: ideal
Temperature stability: high
Susceptible to breakage: yes
Can be cut with scissors: no
Chemical resistance against solvents: high
Chemical resistance against mineral acids and concentrated ammonia: high
Suitability for aqueous detection reagents: depends on phases (layer)

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Aluminium Sheets - ALUGRAM Xtra

Aluminium sheets are easy to handle, lightweight and flexible. High performance silica on ALUGRAM Xtra sheets provides outstanding wettability for precise colourisation results, even with 100% aqueous detection reagents. Moreover, ALUGRAM Xtra sheets are easy to cut with scissors. No flaking of silica occurs.

Thickness (approx.): 0.15mm
Weight and storage requirements: low
Torsional strength: relatively high
Temperature stability: high
Susceptible to breakage: no
Can be cut with scissors: yes
Chemical resistance against solvents: high
Chemical resistance against mineral acids and concentrated ammonia: low
Suitability for aqueous detection reagents: ALUGRAM: low to moderate, ALUGRAM Xtra: moderate to high

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Polyester Sheets – POLYGRAM

Polyester sheets are easy to handle, lightweight and flexible, and can also be cut with scissors. Developed POLYGRAM sheets can also be stored for documentation in laboratory notebooks.

Thickness (approx.): 0.2mm
Weight and storage requirements: low
Torsional strength: low
Temperature stability: maximum 185°C
Susceptible to breakage: no
Can be cut with scissors: yes
Chemical resistance against solvents: high
Chemical resistance against mineral acids and concentrated ammonia: high
Suitability for aqueous detection reagents: good

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Features of modern TLC/HPTLC

The success of thin layer chromatography as a highly efficient microanalytical separation method is based on a large number of advantageous properties:

High sample throughput in a short time
Suitable for screening tests
Pilot procedure for HPLC and Flash chromatography
After separation the analytical information can be stored for a longer period of time (the TLC ready-to-use layer acts as storage medium for data)
Separated substances can be subjected to subsequent analytical procedures (e.g., IR, MS) at a later date
Rapid and cost-efficient optimisation of the separation due to easy change of mobile and stationary phase

TLC and HPTLC are both widely used terms in laboratory environments, but what is the difference? At MACHEREY-NAGEL, we define 'HPTLC' where at least one of the following criteria is being fulfilled:

Layers with particle size 2 to 10μm
Layers prefixed with 'Nano'
Modified layers

Narrow fractionation of HPTLC silica particles allows:

Sharper separations
Shorter developing times
Shorter migration distances
Smaller samples needed
Increased detection sensitivity (compared to TLC)

Catalog Number 10651363

Macherey-Nagel™ Adamant™ Unmodified Standard Silica Layers for TLC, UV254

Catalog Number 10517771

Macherey-Nagel™ Standard SIL G Silica Layers on Alugram™ Aluminum Sheets UV254

Catalog Number 10486471

Macherey-Nagel™ TLC Simultaneous Developing Chamber

1 – 15 of 3,030 results

Macherey-Nagel™ Weighing Papers

Guarantees that weighed goods can be transferred without loss. Macherey Nagel™ Weighing Papers are transparent and smooth on both sides.

Pricing and Availability

Macherey-Nagel™ Glass Laboratory Sprayer

Used as an accessory in thin layer chromatography applications. Macherey-Nagel™ Glass Laboratory Sprayer includes a 100mL, clear glass conical flask with a sprayer-stopper assembly and rubber bulb/tubing.

Pricing and Availability

Macherey-Nagel™ NucleoSpin™ Gel and PCR Clean-up Kit

Clean up PCR reactions and gel extractions with a two-in-one approach. Macherey-Nagel™ NucleoSpin™ Gel and PCR Clean-up Kit is optimized for recovery and elution volume when purifying DNA fragments via both applications.

Pricing and Availability

Macherey-Nagel™ NucleoSpin™ Plasmid Columns for plasmid DNA

Replacement columns for use with NucleoSpin™ Plasmid kits for rapid, small-scale preparation of high-purity, sequencing-grade plasmid DNA.

Pricing and Availability
Specifications

Includes	Columns only
Format	Mini Spin Column
Product Type	NucleoSpin Plasmid lidded Column
For Use With (Equipment)	NucleoSpin™ Plasmid Kit
Final Product Type	Sequencing-grade plasmid DNA
Efficiency	Binding capacity: 50 μg
Sample Type	E. coli Culture
Isolation Technology	Silica Membrane Technology
Sample Volume	2 to 10 mL
Elution Volume	50 μL
For Use With (Application)	Preparation of high-purity plasmid DNA

Macherey-Nagel™ NucleoSpin™ Gel and PCR Clean-up, kit for gel extraction or PCR clean up

Pricing and Availability
Specifications

Format	Mini Spin Column
Efficiency	Typical recovery: 70–95%
Size	50 bp to ∼20 kbp
Isolation Technology	Silica Membrane Technology
Color	pH Indicator: Yellow = correct conditions Green = pH slightly high (adjustment recommended) Blue = pH too high (adjustment necessary)
Purity	A₂₆₀/A₂₈₀: 1.8–1.9
Quantity	1 Kit
Yield	Up to ∼15μg DNA
Test Time	10 min/6 preps

Macherey-Nagel™ NucleoBond™ PC EF Kit Buffer Solutions

Additional supply of buffer for use with NucleoBond™ PC EF kits (PC 500 EF, PC 2000 EF, PC 10000 EF, PC Prep 100) for the purification of endotoxin-free plasmid DNA. Buffer solutions include: S1/S2/S3-EF, N2/N3/N4/N5-EF, TE-EF, and H₂O-EF.

Pricing and Availability
Specifications

Content And Storage	Room Temperature (18°C to 25°C)
CAS	64-17-5d
Form	Liquid
For Use With (Equipment)	NucleoBond™ PC EF kits (PC 500 EF, PC 2000 EF, PC 10000 EF, PC Prep 100)
Color	Colorless
Shelf Life	At least 1 year
For Use With (Application)	Purification of endotoxin-free plasmid DNA

Macherey-Nagel™ MN 85/90 Glass Fiber Filters

Filter organic or inorganic solvents quickly with high particle retention. Macherey Nagel™ MN 85/90 Glass Fiber Filters provide safe filtration of aggressive liquids

Pricing and Availability
Specifications

Thickness (Metric)	0.4 mm
Type	Filter Paper
Basis Weight	90 g/m²
Filtration Time	22sec.
Temperature (Metric) Max	200°C
Quantity	100 Pack
Grade	MN 85/90
Surface Type	Smooth

Macherey-Nagel™ Clear Glass Crimp Neck Vials N20

These crimp neck vials N20 with a bevelled HS crimp neck are used in combination with N20 aluminum closures for Karl Fischer titration on the Metrohm instruments. Certificates of compliance are available on request.

Pricing and Availability

Macherey-Nagel™ Standard SIL G Silica Layers on Polygram™ polyester sheets

Separate non-volatile mixtures with unmodified standard silica layers for TLC (Thin-Layer Chromatography). Standard SIL G silica layers on Polygram™ polyester sheets come in a variety of sizes. Select fluorescent indicator and choose from a variety of pack sizes.

Pricing and Availability
Specifications

Thickness (Metric)	0.2 mm
Pore Size	60 Å
Type	Polyester Sheet
Pore Volume	0.75 mL/g
Fluorescent Indicator	UV254

Macherey-Nagel™ rDNase Set

Recombinant DNase and rDNase Reaction Buffer, for RNA mini preparations with NucleoSpin RNA, NucleoSpin RNA XS, NucleoSpin miRNA, NucleoSpin RNA Blood, NucleoSpin RNA Plant, or NucleoSpin RNA/Protein kits

Pricing and Availability

Macherey-Nagel™ Standard SIL G Silica Layers on Alugram™ Aluminum Sheets UV254

Separate non-volatile mixtures with unmodified standard silica layers for TLC (Thin-Layer Chromatography). Standard SIL G Silica Layers on Alugram™ Aluminum Sheets UV254 come in a variety of sizes.

Pricing and Availability
Specifications

Specific Surface	∼500 m²/g
Pore Size	60 Å
Particle Size	5 to 17 μm
Pore Volume	0.75 mL/g
Fluorescent Indicator	UV254

Macherey-Nagel™ Xtra SIL G Silica Layers on Alugram™ Aluminum Sheets UV254

Separate non-volatile mixtures with unmodified standard silica layers for TLC (Thin-Layer Chromatography). Xtra SIL G Silica Layers on Alugram™ Aluminum Sheets UV254 come in a variety of sizes.

Pricing and Availability
Specifications

Thickness (Metric)	0.20 mm
Specific Surface	∼500 m²/g
Pore Size	60 Å
Particle Size	5 to 17 μm
Type	Aluminum Sheet
Pore Volume	0.75 mL/g
Fluorescent Indicator	UV254

Macherey-Nagel™ Quantofix™ Test Strips

Perform fast, easy analyses on the spot. Macherey-Nagel™ Quantofix™ Test Strips are ready to use semi-quantitative tests that change color depending on the concentration of the analyte in the sample. Read results using the color scale or with the Quantofix™ Relax.