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Corning offers a comprehensive range of innovative, high-quality tools and solutions for life science research and bioproduction. All Corning brands offer consistent, reliable and repeatable results giving you the confidence that you can only get with almost 100 years of expertise in research, product development and manufacturing.
Life Sciences products include consumables (such as plastic vessels, speciality surfaces, cell culture media and serum), as well as general labware and equipment, that are used for advanced cell culture research, bioprocessing, genomics, drug disovery, microbioloby and chemistry. Corning sells life sciences products under these primary brands: Corning™, Falcon™, Axygen™ and Corning Gosselin™.
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At Corning, cells are in our culture. In our continuous effort to improve efficiencies and develop new tools and technologies for life science researchers, we have scientists working in Corning research and development labs across the globe, doing what you do every day.
From seeding starter cultures to expanding cells for assays, our technical experts understand your challenges and your increased need for more reliable cells and cellular material.
It is this expertise, plus a 160-year history of Corning innovation and manufacturing excellence, that puts us in a unique position to offer a beginning-to-end portfolio of high-quality, reliable cell culture consumables.
Whether you’re just getting started in 3D cell culture, looking for proven ways to scale up, or moving to high throughput screening, Corning can help you break through the barriers to creating more in vivo-like environments and predictive models. Quickly and efficiently.
For more than 25 years, Corning has delivered innovations that have advanced the science of 3D cell culture. We pioneered the development of novel tools providing easier access to in vivo-like 3D models, such as Corning Matrigel™ matrix and Transwell™ permeable supports. And we continue to support you with a diverse and evolving portfolio of innovative 3D cell culture products, like the Corning spheroid microplate, as well as workflow solutions, protocols, and expertise.
At Corning, we continuously strive toward improving efficiencies and developing new products and technologies for life science researchers. From assay preparation to storage, our technical experts understand your challenges and your increased need for high-quality products.
It is this expertise, plus a 160-year legacy of Corning innovation and manufacturing excellence, that puts us in a unique position to be able to offer a beginning-to-end portfolio of high-quality, reliable life science consumables.
From research and development to manufacturing, Corning is proud to offer the latest innovative technology to support your advanced therapy applications. From vaccine production to advanced therapy applications, Corning can supply the tools to get you there.
Our cell expansion platforms, from the trusted HYPER™ to CellSTACK™ technologies, are proven to increase efficiency in scale-up, while continuing to deliver reliability and reproducibility, resulting in increased cell viability and yield. Several of our platforms feature closed systems or automation—thereby reducing risk of contamination, variability, and human error.
In our continuous efforts to improve efficiencies and develop new tools and technologies for life science researchers, we have scientists working in Corning research and development labs doing what you do every day, across the globe. From collection to analysis, our technical experts understand your challenges and your need for simplified, efficient, low- to high-throughput genomics processes.
A combination of global manufacturing expertise, extensive use of in-house automation, an unsurpassed commitment to product innovation, and a thorough understanding of your processes enables Corning to offer a beginning-to-end portfolio of high-quality, reliable consumables and reagents for genomics applications.
Electrophoresis is crucial in molecular biology. Corning provides a full range of lab products for sample preparation to analysis, ensuring optimal performance and ease.
Stay vigilant in the lab. Use individual bench top equipment to reduce high-touch shared items, whether preserving cultures or performing essential tasks.
When you need a reliable path from research to bioprocessing try efficient tools like the Corning™ HYPERFlask™ cell culture vessel.
Use Corning cryogenic vials and DMSO media with CoolCell to protect samples in ultra-low temperatures. Choose from various caps and reusable racks.
Connect the cell counter to your device and start the CytoSMART Cloud App. Cloud processing adds features based on user needs. New algorithm resolves cells as small as 4 μm.
Corning offers you a broad and extensive portfolio of vessels across all cell types for every stage of scale up.
Chimeric Antigen Receptor, or CAR T-cells, are genetically modified autologous T-cells that are currently used for immunotherapy to treat certain cancers.
These T-cells are modified to express CARs, which are proteins that allow T-cells to recognize an antigen on targeted tumor cells. Early outcomes from CAR T-cells trials have generated impressive results in patients with refractory or relapsed leukemias and lymphomas 1-2, and research is underway on using CAR T-cells in solid tumors.
CAR T-cells are generated by collecting whole blood from a patient and PBMC (peripheral blood mononuclear cells) are separated and saved while the remaining blood cells and components are returned to the body (leukapheresis). Next, T-cells are enriched from the PBMC population using various methods (e.g., density gradient, size-based fractionation, antibody bead conjugates).
The T-cells are genetically modified with genes of interest, such that they now express CARs, allowing them to target and destroy tumor cells. CAR T-cells are activated and expanded (ex vivo), and in production scale there are additional QA and transportation/delivery steps. Finally, CAR T-cells are infused back to the patient. This may be indirectly to the peripheral circulation or directly to the affected site depending on the tumor type.
T-cell isolation is the process of separating T-cells from other cell types in a biological sample. T-cells can be identified by surface markers like CD3, CD4, and CD8. Cell separation is a critical step in the research process.
Whether you're expanding suspension or adherent cell lines, we offer a full range of cell culture vessels, from 75 mL T-flasks to 50L rocker bags. Our broad and comprehensive portfolio of quality-controlled cell culture vessels allows you to seamlessly scale up with the peace of mind that the products you start with will be suitable for regulated drug manufacturing environments downstream.
Following your scale-up process, it is time to harvest your cells and prepare to move to downstream manufacturing steps or to cryopreserve cells. For cell processing, Corning offers closed system solutions to ensure a contamination-free filtration process. These closed system solutions are ready-to-use, eliminating the time and expense of sourcing and assembling your own closed system. Couple that with sterility assurance and manufacturing compliance, and you have all the tools you need to customize a process to streamline a viable cell collection. For freezing and preserving your cell therapy collection, Corning offers a portfolio of cryogenic storage products, from Corning CoolCell controlled-rate, alcohol-free cell freezing systems to cryogenic vials and bags, all designed to protect your valuable cell lines.